Description
Product Characteristics: IL17F, a member of the IL17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL17F also regulates cartilage matrix turnover and inhibits angiogenesis.
Target Information: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]